NFL Picks - Week 1
| Away | Line | Home |
|---|---|---|
| Bills | -2.5 | Rams |
| Ravens | -7 | Jets |
| Colts | -7 | Texans |
| Eagles | -4 | Lions |
| 49ers | -7 | Bears |
| Browns | +1.5 | Panthers |
| Steelers | +6.5 | Bengals |
| Saints | -5.5 | Falcons |
| Jaguars | +2.5 | Commanders |
| Patriots | +3.5 | Dolphins |
| Giants | +5.5 | Titans |
| Packers | -1.5 | Vikings |
| Raiders | +3.5 | Chargers |
| Chiefs | -6 | Cardinals |
| Buccaneers | -2.5 | Cowboys |
| Broncos | -6.5 | Seahawks |