NFL Picks - Week 16
| Home | Line | Away |
|---|---|---|
| Jets | -2 | Jaguars |
| Bears | +8 | Bills |
| Chiefs | -10 | Seahawks |
| Patriots | +3 | Bengals |
| Vikings | -4.5 | Giants |
| Panthers | +3 | Lions |
| Brows | -2.5 | Saints |
| Titans | -3 | Texans |
| Ravens | -7.5 | Falcons |
| 49ers | -7 | Commanders |
| Cowboys | -5 | Eagles |
| Steelers | -2 | Raiders |
| Dolphins | -3.5 | Packers |
| Rams | +2.5 | Broncos |
| Cardinals | +7.5 | Buccaneers |